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Updated: Jun 2, 2026

Facile Preparation of (2Z,4E)-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate
Published on: June 21, 2017
Ruthenium-catalyzed direct arylations through C-H bond cleavages
Lutz Ackermann1, Rubén Vicente
1Institut for Organische und Biomolekulare Chemie, Georg-August-Universittät Göttingen, Tammanstrasse 2, 37077, Göttingen, Germany. lutz.ackermann@chemie.uni-goettingen.de
Abstract:
Stoichiometric cycloruthenation reactions of substrates containing Lewis-basic functionalities set the stage for efficient ruthenium-catalyzed C-H bond functionalization reactions. Thereby, selective addition reactions of C-H bonds across alkenes or alkynes enabled atom-economical synthesis of substituted arenes. More recently, ruthenium-catalyzed direct arylation reactions were examined, which display an unparalleled scope and, hence, represent economically and environmentally benign alternatives to traditional cross-coupling chemistry.
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