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Types of Membrane Protrusions

Types of Membrane Protrusions

The protrusion of the cell surface is an initial step for several cellular processes, including cell migration, phagocytosis, and neurite outgrowth. These membrane protrusions are a result of cytoskeletal rearrangement. The most widely observed cell protrusions include lamellipodia, pseudopodia, filopodia, microvilli, invadopodia, and podosomes. These protrusions can be of two types — static or dynamic.
The microvilli, an example of stable protrusions, are finger-like projections with a...

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Updated: Jun 2, 2026

Real Time Measurements of Membrane Protein:Receptor Interactions Using Surface Plasmon Resonance (SPR)

Real Time Measurements of Membrane Protein:Receptor Interactions Using Surface Plasmon Resonance (SPR)

Published on: November 29, 2014

pH responsive polymer cushions for probing membrane environment interactions.

Rita J El-Khouri¹, Daniel A Bricarello, Erik B Watkins

¹Department of Chemistry, University of California, Davis, Davis, California 95616, United States.

|April 20, 2011

Summary

This summary is machine-generated.

Researchers developed a simple method to create adaptable lipid membranes on polymer cushions. This system models cellular cytoskeleton interactions and membrane behavior, aiding biophysical studies.

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Last Updated: Jun 2, 2026

Real Time Measurements of Membrane Protein:Receptor Interactions Using Surface Plasmon Resonance (SPR)

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A Nanobar-Supported Lipid Bilayer System for the Study of Membrane Curvature Sensing Proteins in vitro

A Nanobar-Supported Lipid Bilayer System for the Study of Membrane Curvature Sensing Proteins in vitro

Published on: November 30, 2022

Area of Science:

Biophysics
Materials Science
Cell Biology

Background:

Lipid membranes are crucial for cellular functions.
Understanding membrane dynamics and interactions is vital for biophysics.
Existing methods for studying membranes on supports can be limiting.

Purpose of the Study:

To develop a robust method for preparing lipid membranes on dynamically responsive polymer cushions.
To create a model system for studying membrane conformational changes induced by cellular cytoskeleton interactions.
To investigate the potential for tailoring membrane properties for specific environmental responses.

Main Methods:

Preparation of lipid membranes on dynamically responsive polymer cushions.
Structural characterization of the constructed membranes.
Incorporation of protein ion channels to modulate pH response.

Main Results:

A straightforward method for constructing complete, well-packed lipid membranes was established.
Membranes exhibited tunable mobility on the polymer cushion.
The system successfully modeled membrane conformational changes due to simulated cytoskeleton interactions.
Tailoring membrane properties allowed for pH screening or rapid pH response via ion channels.

Conclusions:

The developed system provides a robust platform for studying lipid membranes.
It enables modeling of cytoskeleton-induced membrane dynamics.
This approach facilitates fundamental biophysical studies of membrane properties and interactions, decoupled from rigid supports.