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[Paecilomyces lilacinus--sensitivity to disinfectants]
1Výskumný ústav preventívneho lekárstva, Bratsilava.
Abstract:
In conjunction with nosocomial infection of opthalomycoses in the ophthalmological department, from the enucleated eye and from Ringer solution (used during operations) a fibrous microscopic fungus Paecilomyces lilacinus was isolated. During sensitivity tests of the isolated strain to locally used disinfectants and chemical sterilizing agents it was revealed that the strain was not killed even by the action of higher concentrations of disinfectant solutions, used in our health departments according to instructions of the Ministry of Health of the Slovak Republic. Persteril, although supposed to act as a chemical sterilizing agent 0.5% concentrations and 10 minute exposure, killed the isolated strains only in the course of 30 minutes. Based on tests of the strain Paecilomyces lilacinus it must be foreseen that in health institutions strains of microorganisms may be present which are resistant to these concentrations of disinfectants which are considered effective.
Insights
A microscopic fungus, Paecilomyces lilacinus, caused nosocomial infections in an ophthalmology department. This fungus demonstrated resistance to standard disinfectant concentrations, posing a risk in healthcare settings.
Area of Science:
- Ophthalmology
- Mycology
- Infectious Diseases
Context:
- Nosocomial infections in ophthalmology departments.
- Isolation of Paecilomyces lilacinus from enucleated eyes and Ringer solution.
- Evaluation of disinfectant efficacy against clinical isolates.
Purpose:
- To identify the causative agent of opthalomycoses.
- To assess the susceptibility of Paecilomyces lilacinus to disinfectants.
- To determine the effectiveness of standard disinfectants against resistant microbial strains.
Summary:
- Paecilomyces lilacinus was isolated from patients with nosocomial opthalomycoses.
- The isolated fungus showed resistance to commonly used disinfectant concentrations.
- Standard disinfectants, including Persteril, required prolonged exposure times to inhibit fungal growth.
Impact:
- Highlights the potential for disinfectant-resistant microorganisms in healthcare settings.
- Suggests a need for re-evaluation of disinfection protocols in ophthalmology.
- Emphasizes the importance of identifying and managing resistant fungal pathogens to prevent hospital-acquired infections.