[Postoperative infusion therapy in children]

Area of Science:

• Pediatric Anesthesiology
• Fluid Management
• Hemodynamics

Background:

• Intraoperative fluid management is crucial in pediatric surgery.
• Colloids are frequently used to maintain hemodynamic stability.
• Understanding the impact of different colloids on fluid balance is essential.

Purpose of the Study:

• To compare the effects of Voluven 6% and HAES-steril 10% on hemodynamics and body water distribution in children undergoing surgery.
• To evaluate the efficacy of these colloids in neutralizing anesthetic-induced hemodynamic changes and intraoperative fluid loss.

Main Methods:

• A study involving 40 pediatric patients (3 months to 17 years) divided into two groups.
• Administration of Voluven 6% (5 ml/kg/hour) for blood loss up to 15% of total circulating blood volume (TCBV).
• Administration of HAES-steril 10% (4 ml/kg/hour) for blood loss up to 25% of TCBV.

Main Results:

• Both Voluven 6% and HAES-steril 10% effectively neutralized hemodynamic changes and compensated for fluid loss.
• Voluven 6% administration resulted in a significant decrease in lower limb impedance, indicating increased limb fluid.
• HAES-steril 10% administration led to significant fluid redistribution, with a predominant increase in torso water.

Conclusions:

• Colloid infusion at a 1:3 ratio with crystalloids effectively manages hemodynamics and fluid balance in pediatric surgery.
• Voluven 6% and HAES-steril 10% have distinct effects on body water distribution.
• These findings aid in optimizing fluid management strategies in pediatric surgical patients.