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Published on: January 17, 2018
Suprasellar tuberculoma presenting as panhypopituitarism
Uma Su Sundar1, Vishal V Ramteke, Meghna S Vaidya
1Dept of Medicine, LTM Medical College and General Hospital, Sion, Mumbai-400 022.
The Journal of the Association of Physicians of India
|April 23, 2011
Summary
Suprasellar tuberculomas, rare brain lesions, can cause panhypopituitarism. Early diagnosis and treatment with antitubercular therapy and hormone replacement lead to significant patient recovery.
Area of Science:
- Neurology
- Endocrinology
- Infectious Diseases
Background:
- Suprasellar tuberculomas are rare intracranial tuberculomas.
- They can present with diverse neurological and endocrine symptoms.
Observation:
- A middle-aged male presented with apathy and meningism.
- Neuroimaging revealed suprasellar tuberculomas.
- Endocrinological evaluation indicated panhypopituitarism (hypothyroidism, hypocortisolism, hyperprolactinemia).
Findings:
- Cerebrospinal fluid analysis showed lymphocytic pleocytosis and elevated protein.
- The patient was diagnosed with suprasellar tuberculoma causing panhypopituitarism.
- Antituberculous treatment and hormone replacement were initiated.
Implications:
- This case highlights the importance of considering tuberculosis in the differential diagnosis of suprasellar masses.
- Prompt treatment can lead to clinical improvement and radiological resolution of the tuberculoma.
- Effective management involves a multidisciplinary approach combining infectious disease, endocrine, and neurological care.
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