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Proline-catalysed amination reactions in cyclic carbonate solvents

Christopher Beattie1, Michael North, Pedro Villuendas

  • 1School of Chemistry, Research Centre in Catalysis and Intensified Processing, Bedson Building, University of Newcastle, Newcastle upon Tyne, NE1 7RU, UK.

Molecules (Basel, Switzerland)
|April 23, 2011
PubMed
Summary

Propylene carbonate offers a green alternative to traditional solvents for proline-catalyzed reactions. This sustainable solvent achieves high enantioselectivity in aldehyde and ketone hydrazinations, even with reduced catalyst amounts.

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