Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Internal calcium-binding proteins.

C W Heizmann1, B W Schäfer

  • 1Department of Pediatrics, University of Zürich, Switzerland.

Seminars in Cell Biology
|August 1, 1990
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The KMT2A recombinome of acute leukemias in 2023.

Leukemia·2023
Same author

The MLL recombinome of acute leukemias in 2017.

Leukemia·2017
Same author

Targeting hedgehog signaling reduces self-renewal in embryonal rhabdomyosarcoma.

Oncogene·2015
Same author

The MLL recombinome of acute leukemias in 2013.

Leukemia·2013
Same author

Mechanics of Flexible Needles Robotically Steered through Soft Tissue.

The International journal of robotics research·2010
Same author

p21 Downregulation is an important component of PAX3/FKHR oncogenicity and its reactivation by HDAC inhibitors enhances combination treatment.

Oncogene·2010
Same journal

Granulocyte clearance by apoptosis in the resolution of inflammation.

Seminars in cell biology·1995
Same journal

Signalling heterogeneity as a contributing factor in macrophage functional diversity.

Seminars in cell biology·1995
Same journal

Neutrophil proteinases and matrix degradation. The cell biology of pericellular proteolysis.

Seminars in cell biology·1995
Same journal

NADPH oxidase and the respiratory burst.

Seminars in cell biology·1995
Same journal

Intracellular signaling in neutrophil priming and activation.

Seminars in cell biology·1995
Same journal

Granulocyte adhesion molecules--structure/function relationships.

Seminars in cell biology·1995
See all related articles

Calcium ions (Ca2+) regulate cellular functions. Impaired calcium homeostasis is linked to diseases, with signaling proteins like EF-hand and Ca2+-dependent/phospholipid-binding proteins playing crucial roles.

Area of Science:

  • Cellular Biology
  • Biochemistry
  • Molecular Biology

Background:

  • Calcium ions (Ca2+) are critical regulators of numerous cellular processes.
  • Disruptions in calcium homeostasis are associated with various diseases.
  • Intracellular Ca2+ signaling relies on specific protein families.

Purpose of the Study:

  • To summarize the protein and gene structures of key intracellular Ca2+ signaling proteins.
  • To explore the potential functional roles of these Ca2+-binding proteins.

Main Methods:

  • Literature review and data synthesis on EF-hand proteins.
  • Literature review and data synthesis on Ca2+-dependent and phospholipid-binding proteins.

Main Results:

Related Experiment Videos

  • Detailed overview of the structural characteristics of EF-hand proteins.
  • Detailed overview of the structural characteristics of Ca2+-dependent and phospholipid-binding proteins.
  • Summary of the diverse functional roles attributed to these protein families in cellular signaling.

    • Conclusions:

    • EF-hand and Ca2+-dependent/phospholipid-binding proteins are essential for intracellular Ca2+ signal transduction.
    • Understanding these proteins' structures and functions is vital for comprehending calcium homeostasis and related diseases.