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Related Experiment Video

Updated: Jun 2, 2026

Microfluidic Bioprinting for Engineering Vascularized Tissues and Organoids
08:22

Microfluidic Bioprinting for Engineering Vascularized Tissues and Organoids

Published on: August 11, 2017

Aqueous biphasic microprinting approach to tissue engineering.

Hossein Tavana, Shuichi Takayama

    Biomicrofluidics
    |April 28, 2011
    PubMed
    Summary
    This summary is machine-generated.

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    A new microprinting technology enables gentle, contact-free placement of cells and biomolecules onto biological surfaces. This biomaterial printing method supports tissue engineering and cell interaction studies with high viability.

    Area of Science:

    • Biotechnology
    • Materials Science
    • Cell Biology

    Background:

    • Developing advanced methods for precise biomaterial deposition is crucial for cell biology and tissue engineering.
    • Existing techniques often struggle with maintaining cell viability and achieving complex spatial arrangements on biological substrates.

    Purpose of the Study:

    • To introduce and detail a novel microtechnology for printing biomaterials, including cells and biomolecules, onto biological surfaces.
    • To demonstrate the capability of this technique for applications in cell interaction studies and tissue engineering.

    Main Methods:

    • Utilized immiscible aqueous solutions of two biopolymers for spatially defined printing.
    • Leveraged minimal interfacial tension and density differences for a contact-free printing process.

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    Bioprinting of Cartilage and Skin Tissue Analogs Utilizing a Novel Passive Mixing Unit Technique for Bioink Precellularization

    Published on: January 3, 2018

    Viability of Bioprinted Cellular Constructs Using a Three Dispenser Cartesian Printer
    07:05

    Viability of Bioprinted Cellular Constructs Using a Three Dispenser Cartesian Printer

    Published on: September 22, 2015

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    Last Updated: Jun 2, 2026

    Microfluidic Bioprinting for Engineering Vascularized Tissues and Organoids
    08:22

    Microfluidic Bioprinting for Engineering Vascularized Tissues and Organoids

    Published on: August 11, 2017

    Bioprinting of Cartilage and Skin Tissue Analogs Utilizing a Novel Passive Mixing Unit Technique for Bioink Precellularization
    09:03

    Bioprinting of Cartilage and Skin Tissue Analogs Utilizing a Novel Passive Mixing Unit Technique for Bioink Precellularization

    Published on: January 3, 2018

    Viability of Bioprinted Cellular Constructs Using a Three Dispenser Cartesian Printer
    07:05

    Viability of Bioprinted Cellular Constructs Using a Three Dispenser Cartesian Printer

    Published on: September 22, 2015

  • Deposited cells and biomolecules onto existing cell layers and extracellular matrix hydrogels.

    • Main Results:

    • Achieved spatially defined placement of cells and biomolecules with full viability and functionality.
    • Demonstrated the ability to create arbitrarily shaped patterns and microarrays.
    • Successfully printed non-gel-embedded cells directly onto existing cell layers.

    Conclusions:

    • This microprinting technology offers a gentle, effective method for patterning biological materials on living surfaces.
    • The technique is highly suitable for investigating cell-cell and cell-material interactions.
    • It presents a promising approach for tissue engineering applications requiring patterned multicellular organization with minimal scaffolding.