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Related Concept Videos

Role of Skin in Vitamin D Synthesis01:23

Role of Skin in Vitamin D Synthesis

The skin plays a crucial role in the synthesis of vitamin D, a vital nutrient for various physiological processes in the body. Vitamin D is unique because it can be synthesized in the skin through a series of chemical reactions triggered by exposure to ultraviolet B (UVB) radiation from sunlight.
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin D3(cholecalciferol).
Connective Tissue Cell Types01:22

Connective Tissue Cell Types

Connective tissue develops from the mesoderm of a developing embryo and consists of cells, fibers, and ground substance: a gel-like material containing large complexes of carbohydrates and proteins. Connective tissue was first identified as a separate tissue family in the 18th century, and Johannes Peter Muller coined the term connective tissue.
Fat cells (adipocytes), smooth muscle cells (myoblasts), and bone cells (osteoblasts) are some connective tissue cell types. Some immune system cells...
Role of Vitamins in Maintaining Bone Health01:25

Role of Vitamins in Maintaining Bone Health

The growth and maintenance of bone are regulated by a combination of nutritional factors, including vitamins, such as vitamin A, B12, C, D, and K.
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
Vitamins01:30

Vitamins

Vitamins, derived from the Latin word for life, are essential organic substances required in small quantities for optimal growth and overall well-being. Unlike other organic nutrients, vitamins don't act as sources of energy or building materials but rather facilitate these nutrients' utilization by the body. Vitamins are predominantly coenzymes, assisting enzymes in specific chemical actions, like the oxidation of glucose for energy involving B vitamins. Most vitamins are not produced in our...
Pharmacodynamics in Geriatric Patients: Effects of Age01:27

Pharmacodynamics in Geriatric Patients: Effects of Age

Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...

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Related Experiment Video

Updated: Jun 2, 2026

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data
10:46

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data

Published on: December 9, 2015

Vitamin D: Lessons from the veterans population.

Tariq Islam1, Prith Peiris, Rebecca J Copeland

  • 1Department of Internal Medicine, East Tennessee State University, Johnson City, TN, USA.

Journal of the American Medical Directors Association
|April 30, 2011
PubMed
Summary

Vitamin D deficiency affects 40% of veterans, increasing healthcare costs. Higher doses than currently recommended may be needed to achieve adequate vitamin D levels for optimal health benefits.

Related Experiment Videos

Last Updated: Jun 2, 2026

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data
10:46

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data

Published on: December 9, 2015

Area of Science:

  • Endocrinology
  • Public Health
  • Geriatrics

Background:

  • Vitamin D deficiency (25(OH)D < 20 ng/mL) is prevalent in approximately 40% of veterans, correlating with elevated healthcare expenditures and service utilization.
  • Higher prevalence is observed in specific veteran subgroups, including ethnic minorities, individuals with chronic illnesses, and nursing home residents.
  • Inadequate sunlight exposure and poor dietary intake are primary contributors, with deficiency noted even in those adhering to recommended supplement dosages.

Purpose of the Study:

  • To highlight the significant prevalence of vitamin D deficiency in the veteran population.
  • To underscore the inadequacy of current testing and monitoring practices for vitamin D status.
  • To emphasize the recognized health benefits of achieving vitamin D repletion and the need for improved management strategies.

Main Methods:

  • Review of existing literature on vitamin D deficiency prevalence and management in veterans.
  • Analysis of factors contributing to vitamin D deficiency, including sunlight exposure, diet, and supplementation.
  • Evaluation of current testing and monitoring guidelines and their impact on patient outcomes.

Main Results:

  • A substantial percentage of veterans exhibit vitamin D deficiency, leading to increased healthcare costs.
  • Current recommended daily intake may be insufficient to achieve therapeutic 25(OH)D levels (30-100 ng/mL) in many individuals.
  • Suboptimal testing and monitoring protocols hinder the effective management of vitamin D deficiency.

Conclusions:

  • Achieving adequate vitamin D status in US veterans is a critical health objective with potential to improve longevity.
  • Evidence-based guidelines for vitamin D testing and monitoring are urgently needed to optimize patient care.
  • The recognized benefits of vitamin D repletion across cardiovascular, immunological, infectious, and oncological systems necessitate improved management strategies.