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Updated: Jun 2, 2026

Identification and Dissection of Diverse Mouse Adipose Depots
Published on: July 11, 2019
[Adipocytes and bone metabolism]
Hironori Waki1, Toshimasa Yamauchi, Takashi Kadowaki
1Department of Diabetes and Metabolic Diseases, the University of Tokyo.
Abstract:
Adipocytes, osteoblasts and chondrocytes derive from common mesenchymal stem cells. A number of factors were reported to regulate differentiation of multiple cell types among adipocytes, osteoblasts and chondrocytes. Thiazolidinediones are prescribed to treat diabetes in obese subjects, but recent clinical data suggested that it increases a risk of bone fracture especially in postmenopausal women. Here, we will review recent advances in the researches of mutual connection between adipocytes and bone metabolism.
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