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Related Concept Videos

Overview of Exosomes01:36

Overview of Exosomes

Exosomes are stable, lipid bilayer-enclosed vesicles capable of crossing biological barriers. They can carry a wide range of molecules required for intercellular communication. Once exosomes are released from the cell where they originated, they enter a recipient cell through various pathways such as fusion, receptor-mediated endocytosis, macropinocytosis, and phagocytosis.
Stahl et al. discovered exosomes in 1983, but the exosomes were initially considered waste products released from the...
Proteomics01:33

Proteomics

A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term proteomics...
Microbiota of the Urogenital Tract01:28

Microbiota of the Urogenital Tract

The human urogenital system, once thought to be sterile in healthy individuals, is now recognized as a complex microbial habitat. Advancements in molecular sequencing techniques have revealed that even in healthy adults, the kidneys and bladder harbor microbial populations similar to those found in the distal urethra, albeit in much lower abundance. These resident microorganisms, while generally innocuous, can become opportunistic pathogens under conditions that alter the urogenital...

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Related Experiment Video

Updated: Jun 2, 2026

A Modified Precipitation Method to Isolate Urinary Exosomes
05:05

A Modified Precipitation Method to Isolate Urinary Exosomes

Published on: January 16, 2015

Urinary exosomes and proteomics.

Pyong-Gon Moon1, Sungyong You, Jeong-Eun Lee

  • 1Department of Molecular Medicine, Cell and Matrix Biology Research Institute, School of Medicine, Kyungpook National University, Daegu 700-422, Republic of Korea.

Mass Spectrometry Reviews
|May 6, 2011
PubMed
Summary
This summary is machine-generated.

Urinary exosomes, released from cells lining the urinary tract, are promising for identifying disease biomarkers. Proteomic analysis of these exosomes can reveal cellular processes linked to urogenital diseases.

More Related Videos

Proteomic Profile of EPS-Urine through FASP Digestion and Data-Independent Analysis
14:48

Proteomic Profile of EPS-Urine through FASP Digestion and Data-Independent Analysis

Published on: May 8, 2021

Related Experiment Videos

Last Updated: Jun 2, 2026

A Modified Precipitation Method to Isolate Urinary Exosomes
05:05

A Modified Precipitation Method to Isolate Urinary Exosomes

Published on: January 16, 2015

Proteomic Profile of EPS-Urine through FASP Digestion and Data-Independent Analysis
14:48

Proteomic Profile of EPS-Urine through FASP Digestion and Data-Independent Analysis

Published on: May 8, 2021

Area of Science:

  • Urology
  • Biochemistry
  • Molecular Biology

Background:

  • Proteomics has identified abundant urinary proteins as potential disease biomarkers.
  • Current biomarkers lack specificity for cellular process perturbations in urogenital diseases.

Purpose of the Study:

  • To explore urinary exosomes as a novel source for disease biomarker discovery.
  • To investigate the potential of urinary exosome proteomic analysis in understanding urogenital disease pathogenesis.

Main Methods:

  • Proteomic analysis of urinary exosomes.
  • Investigating exosome origin and release within the urinary tract.

Main Results:

  • Urinary exosomes are secreted by epithelial cells throughout the urinary tract.
  • Exosomes may contain proteins reflecting cellular processes in donor cells.
  • Proteomic analysis of urinary exosomes aids biomarker identification.

Conclusions:

  • Urinary exosomes represent a valuable resource for developing novel biomarkers.
  • Studying urinary exosomes enhances understanding of urogenital disease pathophysiology.
  • Exosomes offer a non-invasive window into cellular changes in urogenital diseases.