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Updated: Jun 2, 2026

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Phthalic Acid Ester-Binding DNA Aptamer Selection, Characterization, and Application to an Electrochemical Aptasensor
Published on: March 21, 2018
Analyte-induced formation of partial duplexes for the preparation of a label-free electrochemiluminescent aptasensor
Yue Zhao1, Xi-Wen He, Xue-Bo Yin
1Research Center for Analytical Sciences, College of Chemistry, Nankai University, Tianjin, 300071, PR. China.
Abstract:
Analyte-induced formation of partial duplexes was used for biosensor development with cocaine as a model. The cocaine-aptamer interaction resulted in formation of a partial double strand section in the aptamer, where Ru(phen)(3)(2+) was intercalated for electrochemiluminescent analysis of cocaine.

