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Updated: Jun 2, 2026

Preparation of Contiguous Bisaziridines for Regioselective Ring-Opening Reactions
Published on: July 28, 2022
Solvent controlled mechanistic dichotomy in a Au(III)-catalyzed, heterocyclization triggered, Nazarov reaction
Marie E Krafft1, Dinesh V Vidhani, John W Cran
1Department of Chemistry and Biochemistry, Florida State University, Tallahassee, FL 32306, USA. mek@chem.fsu.edu
Abstract:
Tandem Au(III)-catalyzed heterocyclization/Nazarov cyclizations leading to substituted carbocycle fused furans are described. An interesting dichotomy of reaction pathways as a function of solvent, confirmed by the isolation and trapping of reaction intermediates, provided a basis for computational studies that supported the experimental findings.
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