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Related Concept Videos

Ethical Issues01:27

Ethical Issues

Nurses are essential in patient care, upholding the ethical principles of their profession and effectively navigating ethical dilemmas. Neglecting ethical issues can lead to inadequate patient care, compromised therapeutic relationships, and moral distress among healthcare workers.
Ethical Concerns in Healthcare:
Ethical Dilemmas II01:30

Ethical Dilemmas II

Resolving an ethical dilemma in healthcare involves a systematic approach that considers every aspect of the issue, respecting both the patient's needs and values and the healthcare professional's ethical obligations. Here are potential steps to resolve an ethical dilemma:
Ethical Dilemmas I01:17

Ethical Dilemmas I

Ethical dilemmas in nursing are of utmost importance, as they often arise from the tension between adhering to core ethical principles and the practical realities of healthcare delivery. These dilemmas require nurses to navigate complex situations where competing ethical considerations pull them in different directions.
Let us explore some examples to understand the potentially complex moral decisions nurses face.
Take the case of caring for minors, particularly in areas related to reproductive...
Drug Product Performance: In Vitro–In Vivo Correlation01:20

Drug Product Performance: In Vitro–In Vivo Correlation

In pharmaceutical development, it's crucial to establish a predictive in vitro–in vivo correlation (IVIVC) for two or more formulations to gain a comprehensive understanding of release properties. IVIVC reduces the need for costly in vivo studies and facilitates the establishment of meaningful dissolution specifications with significant cost savings and decreased regulatory burden. Furthermore, a meaningful IVIVC should predict Cmax and AUC within 20%, aligning with FDA guidance while adhering...
Immune Response Against Viral Pathogens01:29

Immune Response Against Viral Pathogens

The immune system's response to viral infections is a complex and coordinated process involving natural killer (NK) cells, T cell-mediated responses, and antibody-mediated responses.
NK Cells
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Endocarditis IV: Nursing Management01:29

Endocarditis IV: Nursing Management

Infective endocarditis (IE) is a chronic infection of the heart's endocardium, primarily affecting the heart valves. A detailed nursing assessment for a patient with IE involves collecting subjective and objective data to ensure an accurate diagnosis and timely intervention.Subjective DataThe nurse gathers information about the patient's symptoms and complaints during the subjective assessment. Patients with infective endocarditis often report non-specific symptoms that can mimic other...

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Updated: Jun 2, 2026

OP-IVM: Combining In vitro Maturation after Oocyte Retrieval with Gynecological Surgery
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OP-IVM: Combining In vitro Maturation after Oocyte Retrieval with Gynecological Surgery

Published on: May 9, 2021

Controversies in IVM.

Shauna Leigh Reinblatt1, Weon-Young Son, Einat Shalom-Paz

  • 1MUHC Reproductive Center, Department of Obstetrics and Gynecology, Royal Victoria Hospital, Montreal, Quebec, Canada, H3A 1A1. shauna.reinblatt@muhc.mcgill.ca

Journal of Assisted Reproduction and Genetics
|May 11, 2011
PubMed
Summary
This summary is machine-generated.

Gonadotropin priming and hCG trigger timing benefit oocyte retrieval in certain patients. Further research is needed for optimal protocols in ovarian stimulation, endometrial preparation, and luteal support.

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Area of Science:

  • Reproductive Endocrinology
  • In Vitro Fertilization
  • Ovarian Physiology

Background:

  • Optimizing ovarian stimulation protocols is crucial for successful in vitro fertilization (IVF).
  • Key areas of controversy include gonadotropin priming, human chorionic gonadotropin (hCG) trigger timing, and luteal phase support.
  • Understanding these factors can improve oocyte yield and maturation.

Purpose of the Study:

  • To review the current evidence on gonadotropin priming and hCG trigger benefits and timing.
  • To explore ideal protocols for endometrial preparation and luteal support in IVF cycles.
  • To identify areas requiring further research in assisted reproductive technologies.

Main Methods:

  • A comprehensive literature review was conducted.
  • Evidence regarding ovarian stimulation, oocyte retrieval, and luteal support was analyzed.
  • Focus was on studies addressing controversial aspects of IVF protocols.

Main Results:

  • Gonadotropin priming with hCG benefits patients with normal ovaries.
  • For PCOS patients, 10,000 IU hCG 38 hours prior to retrieval enhances oocyte maturation and yield.
  • Gonadotropin priming may also benefit PCOS patients; ideal hCG trigger is at 10-12 mm leading follicle size, with limited data on luteal support.

Conclusions:

  • Well-designed studies are needed to establish optimal protocols for oocyte priming, retrieval timing, endometrial preparation, and luteal support.
  • Future research should integrate clinical and basic science principles of ovarian, follicular, and endometrial physiology.
  • Standardizing these protocols can enhance IVF success rates.