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Related Experiment Video

Updated: Jun 2, 2026

Brain Infarct Segmentation and Registration on MRI or CT for Lesion-symptom Mapping

Brain Infarct Segmentation and Registration on MRI or CT for Lesion-symptom Mapping

Published on: September 25, 2019

When a brain lesion necessitates chest CT.

Pasquale F Finelli¹

¹Department of Neurology, Hartford Hospital and University of Connecticut School of Medicine, Hartford, CT 06102-5037, USA. pfinell@harthosp.org

Connecticut Medicine

|May 13, 2011

Summary

This summary is machine-generated.

Brain lesions can be difficult to diagnose, especially when symptoms are unclear. A chest CT scan helped identify a rare fungal infection (cerebral cryptococcoma) when other tests were negative.

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A Micro-CT-based Method for Characterizing Lesions and Locating Electrodes in Small Animal Brains

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Published on: November 8, 2018

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Brain Infarct Segmentation and Registration on MRI or CT for Lesion-symptom Mapping

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A Micro-CT-based Method for Characterizing Lesions and Locating Electrodes in Small Animal Brains

A Micro-CT-based Method for Characterizing Lesions and Locating Electrodes in Small Animal Brains

Published on: November 8, 2018

Area of Science:

Neurology
Infectious Diseases
Radiology

Background:

Brain lesions can be the first sign of systemic disease, posing diagnostic challenges.
Neuroimaging may be nonspecific, and other organ involvement might be absent.
Chest CT is not always considered when chest X-rays are negative.

Observation:

A patient presented with nonspecific clinical and neuroimaging findings suggestive of brain lesions.
Initial tests, including chest X-ray and serology, were negative.
Brain imaging was abnormal but not typical of a primary brain process.

Findings:

Computerized tomography (CT) of the chest identified additional lesion sites.
Chest CT led to a lung biopsy, confirming cerebral cryptococcoma.
This diagnosis was made despite negative chest X-ray and serology.

Implications:

Chest CT is a valuable tool for diagnosing systemic diseases presenting as brain lesions.
Consider chest CT in patients with unexplained brain imaging abnormalities, even with a negative chest X-ray.
Early diagnosis through advanced imaging can guide appropriate treatment for systemic infections affecting the brain.