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MR Imaging Patterns and Prognosis in Powassan Virus Encephalitis.
1Department of Neurology, Hartford Hospital and University of Connecticut School of Medicine, Hartford, CT.
The Neurologist
|October 15, 2023
Summary
Powassan virus (POWV) encephalitis, a North American tick-borne illness, often shows a cerebellar-dominant pattern on MR imaging. This pattern is linked to poor outcomes but may respond to steroids.
Area of Science:
- Neurology
- Infectious Diseases
- Radiology
Background:
- Powassan virus (POWV) encephalitis is a significant arbovirus infection endemic to North America.
- It is the sole tick-borne encephalitis serogroup found in mainland North America.
- Current understanding of MR imaging patterns and outcomes in POWV encephalitis is limited due to varied and nonspecific findings.
Conclusions:
- A cerebellar-dominant MR imaging pattern is a common finding in Powassan virus encephalitis.
- This pattern indicates a poor prognosis.
- Early recognition of this MR pattern can guide management, potentially shifting from supportive care to life-saving interventions.
