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Recent advances in the synthesis of sesquiterpenolides from Umbelliferae

Francisco M Guerra1, F Javier Moreno-Dorado, Zacarías D Jorge

  • 1Departamento de Química Orgánica, Universidad de Cádiz, Facultad de Ciencias, Pol. Río San Pedro s/n, 11510 Puerto Real, Cádiz, Spain.

Natural Product Communications
|May 13, 2011
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Sulfides are the sulfur analog of ethers, just as thiols are the sulfur analog of alcohol. Like ethers, sulfides also consist of two hydrocarbon groups bonded to the central sulfur atom. Depending upon the type of groups present, sulfides can be symmetrical or asymmetrical. Symmetrical sulfides can be prepared via an SN2 reaction between 2 equivalents of an alkyl halide and one equivalent of sodium sulfide.