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Updated: Jun 2, 2026

Granulocyte-dependent Autoantibody-induced Skin Blistering
Published on: October 12, 2012
[Adult onset xanthogranuloma in a 73-year-old woman]
Marie Louise von Sperling1, Hilde Høimyr
1Plastikkirurgisk Afdeling, Aarhus Universitetshospital, Aalborg Sygehus, 9000 Aalborg, Denmark. malovs@rn.dk
Abstract:
Adult onset xanthogranuloma (AOX) is a rare benign xanthogranulomatous disease with unknown aetiology and incidence. AOX presents as yellow-brownish skin tumours of different sizes, mostly as solitary lesions, but also as multiple lesions with predilection areas on the face and collum. We here present the case of a 73-year-old woman, who was treated for third and fourth facial AOX recurrences by surgical excisions at the Department of Plastic Surgery, Aalborg Hospital. Due to the rare occurrence of AOX, a prospective evaluation of its treatment is hardly feasible. Oncological, dermatological and surgical treatment of AOX has been described in the literature.
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