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Updated: Jun 2, 2026

Assessing the Innate Sensing of HIV-1 Infected CD4+ T Cells by Plasmacytoid Dendritic Cells Using an Ex vivo Co-culture System.
Published on: September 1, 2015
HIV dermatology in Canada: cutaneous disease burden and demographic characteristics of a specialized urban practice
Jonathan L Shapero1, Jasmine Leslie, Gillian C de Gannes
1Department of Dermatology and Skin Science, University of British Columbia, Vancouver, BC. jshapero@gmail.com
Background:
The introduction of antiretroviral therapies has changed the pattern of cutaneous disease in individuals infected with human immunodeficiency virus (HIV).
Objective:
To assess demographic characteristics, severity of immunosuppression, and frequency of dermatologic disorders in patients presenting to a Canadian specialized HIV dermatology practice.
Methods:
A cross-sectional study was performed of 183 consecutive outpatient and inpatient consultations to a single HIV dermatology practice from January 2007 to December 2008.
Results:
One hundred sixty-three (88%) patients were male, with an average age of 45. Forty-six patients were not on antiretroviral therapy. Verruca was the most common diagnosis, seen in 29 patients, followed by dermatophyte infection, seen in 27. Patients with a low CD4 count (p = .0001) and a high viral load (p = .0043) were more likely to present with an HIV-specific dermatosis.
Conclusion:
Cutaneous infections were the most common diagnoses in this cross section. Classic HIV dermatoses were seen more frequently in those with more advanced disease owing to HIV infection.
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