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Updated: Jun 2, 2026

Freezing, Thawing, and Packaging Cells for Transport

Freezing, Thawing, and Packaging Cells for Transport

Published on: July 2, 2008

Packaging Considerations for Biopreservation.

Erik J Woods¹, Sreedhar Thirumala

¹General BioTechnology, LLC, Indiana University School of Medicine, Indianapolis, IN, USA.

Transfusion Medicine and Hemotherapy : Offizielles Organ Der Deutschen Gesellschaft Fur Transfusionsmedizin Und Immunhamatologie

|May 14, 2011

Summary

This summary is machine-generated.

The CellSeal® closed system cryovial offers excellent closure integrity and stability for biopreservation and biobanking. This vial is suitable for storing cell therapy products, ensuring sample viability during cryopreservation.

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Area of Science:

Biopreservation and Biobanking
Cell Therapy Packaging
Cryopreservation Technologies

Background:

Effective biopreservation requires container systems with closure integrity, sample stability, and contamination-free access.
Current biobanking practices necessitate long-term sample stability and adherence to regulatory standards like current good manufacturing/tissue practice (cGTP).

Purpose of the Study:

To evaluate the suitability of a novel vial-based container system (CellSeal®) for biopreservation and biobanking.
To compare the performance of the CellSeal® closed system cryovial against standard screw cap vials.

Main Methods:

The CellSeal® system was assessed for durability and closure integrity during simulated transportation.
Functional viability of cryopreserved mesenchymal stem cells within the CellSeal® vials was evaluated.
Comparison was made against standard screw cap vials for performance metrics.

Main Results:

The CellSeal® system demonstrated high suitability for biopreservation and biobanking applications.
Hermetic sealing and stability were maintained through cryopreservation and biobanking procedures.
The system proved effective in preserving the functional viability of mesenchymal stem cells.

Conclusions:

The CellSeal® closed system cryovial is a highly suitable container for biopreservation and biobanking.
This vial-based system supports cGTP requirements and offers potential ease of delivery for caregivers.
It serves as an effective container for clinical and commercial cell therapy products requiring small-volume freezing.