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[CRP and micro-albumin: new markers of cardiovascular risk in type 2 diabetes]
M El Oudi1, Z Aouni, H Ouertani
1Laboratoire de biochimie, hôpital militaire principal d'instruction, Montfleury, Tunis, Tunisie. doc mo@ymail.com
Introduction:
Type 2 diabetes is a chronic disease associated to the presence of multiple risk factors. Among recently studied factors we cite PCR and micro-albumin.
Objective:
In the present study we intend to determine the correlation between urine albumin excretion rate, CRP levels and type of vascular complications in type 2 diabetes.
Patients And Methods:
We recruited 48 type 2 diabetic subjects subdivided into three groups according to the type of vascular complications (GI: type 2 diabetics without complications, GII: type 2 diabetics with microvascular complications and GIII: type 2 diabetics with macrovascular complications).
Results:
We found a significant elevated levels of CRP and micro-albumin (P<0.05) when we compared diabetics with vascular complications to those without any complications. Diabetics with macrovascular complications have the highest levels of CRP and micro-albumin. Significant positive correlation was found between CRP and micro-albumin levels in a total group of diabetics (r=0.32; P<0.05).
Conclusion:
The determination of CRP and microalbumin levels represents an interest in the screening of cardiovascular disease in type 2 diabetics.
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