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Updated: Jun 2, 2026

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
Published on: August 30, 2018
Delivering outpatient antibiotic therapy (OPAT) in an Acute Medical Unit
Yin May Yan1, Manjit Singh, Karl Tonks
1Consultant in Acute Medicine and Clinical Pharmacology and Therapeutics, City Hospital, Dudley Road, Birmingham B18 7QH.
Abstract:
Outpatient antibiotic therapy (OPAT) is being developed and practised in an increasing number of acute hospitals within the United Kingdom. This article is a review of the OPAT service delivered by a large inner city hospital over the last two years. The service demonstrates the key elements of OPAT demonstrating different delivery models, aspects of patient selection, spectrum of infections treated, choice and delivery of antimicrobials, efficacy, patient safety, outcomes, and the cost-effectiveness of this programme.
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