Related Experiment Video
Updated: Jun 2, 2026

Modeling Stroke in Mice - Middle Cerebral Artery Occlusion with the Filament Model
Published on: January 6, 2011
Not just a 'simple stroke'
Wendy Russell1, William Taylor, Gautamanada Ray
1MBChB(Ed), MRCP. StR4 in General Internal Medicine (Acute). Monklands Hospital. Monkscourt Avenue, Airdrie, ML6 0JS. wends@doctors.org.uk
Abstract:
A 51-year-old man presenting with left arm weakness and slurred speech was referred to the acute medical team. Admission chest X-ray showed a cavitating lesion, which had not been present 2 weeks earlier. Systemic enquiry elicited a 2 month prodromal illness and back pain. Urgent CT of his head and chest revealed evidence of thoracic discitis spreading anteriorly into a pleural-based lung abscess and an intracerebral abscess causing his neurological deficit. He was transferred for urgent craniotomy and evacuation of a Streptococcus milleri abscess. Following several weeks of neurosurgical care and antibiotics he made a near full recovery.
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