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Updated: Jun 1, 2026
06:46
Facile Preparation of (2Z,4E)-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate
Published on: June 21, 2017
2-[(E)-(1H-Pyrrol-2-ylmethyl-idene)hydrazinyl]pyridine monohydrate
Summary
This study details the crystal structure of a hydrate, C(10)H(10)N(4)·H(2)O. Hydrogen bonding interactions involving a water molecule influence the molecular conformation and facilitate the formation of supramolecular arrays.
Area of Science:
- Crystallography
- Supramolecular Chemistry
- Organic Chemistry
Background:
- Understanding the solid-state structure of organic molecules is crucial for predicting their properties.
- Hydration can significantly alter the packing and conformation of organic compounds.
Purpose of the Study:
- To elucidate the crystal structure of the title hydrate, C(10)H(10)N(4)·H(2)O.
- To investigate the role of water molecules in the supramolecular assembly.
Main Methods:
- Single-crystal X-ray diffraction was employed to determine the molecular and crystal structure.
- Analysis of hydrogen bonding networks was performed.
Main Results:
- The crystal structure reveals a dihedral angle of 11.08° between the pyridine and pyrrole rings.
- Pyridine and pyrrole nitrogen atoms are positioned on the same side, stabilized by hydrogen bonds with the water molecule.
- Intermolecular hydrogen bonds (O-H⋯N and N-H⋯O) lead to the formation of supramolecular arrays in the ab plane.
Conclusions:
- The water molecule plays a key role in stabilizing the twisted conformation of the hydro-zone derivative.
- Hydrogen bonding interactions are essential for the formation of extended supramolecular structures in the solid state.
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