(E)-N'-(2-Chloro-5-nitro-benzyl-idene)-4-methoxy-benzohydrazide
The crystal structure of a novel benzohydrazide derivative was determined. Molecules adopt a trans configuration and form hydrogen-bonded chains in the solid state, revealing insights into intermolecular interactions.
Area of Science:
- Crystallography
- Organic Chemistry
- Materials Science
Background:
- Benzohydrazide derivatives are important scaffolds in medicinal chemistry and materials science.
- Understanding the solid-state structure is crucial for predicting material properties and designing new compounds.
Purpose of the Study:
- To elucidate the crystal structure of a specific C(15)H(12)ClN(3)O(4) compound.
- To investigate the molecular conformation and intermolecular interactions in the solid state.
Main Methods:
- Single-crystal X-ray diffraction was employed to determine the molecular and crystal structure.
- Analysis of bond lengths, bond angles, and dihedral angles provided conformational details.
- Intermolecular interactions, such as hydrogen bonding, were identified and characterized.
Main Results:
- The title compound, C(15)H(12)ClN(3)O(4), exhibits a non-planar benzohydrazide group.
- The molecule adopts a trans configuration around the methylidene unit.
- A small dihedral angle (0.4°) between the two substituted benzene rings was observed.
- Intermolecular N-H⋯O hydrogen bonds link molecules into chains parallel to the c axis.
Conclusions:
- The study provides a detailed structural characterization of the title compound.
- The observed molecular conformation and hydrogen bonding patterns offer insights into crystal packing and intermolecular forces.
- This structural data can inform future research on related benzohydrazide derivatives for potential applications.
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