Related Experiment Video
Updated: Jun 1, 2026
07:36
Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats
Published on: November 20, 2015
Prematurity: is it a risk factor for striae distensae?
Kiymet Handan Kelekci1, Sefa Kelekci, Emre Destegul
1Dermatology Clinics, Numune Education and Research Hospital, Seyhan Practice Center, Adana, Turkey. sefakelekci@gmail.com
International Journal of Dermatology
|May 19, 2011
Summary
Premature birth is a significant risk factor for striae distensae (SD), commonly known as stretch marks. Women born prematurely exhibit a higher prevalence of SD compared to those born at term.
Area of Science:
- Dermatology
- Obstetrics and Gynecology
- Public Health
Background:
- Striae distensae (SD) are a common skin condition linked to structural changes affecting skin elasticity.
- The precise causes of SD remain incompletely understood.
Purpose of the Study:
- To investigate premature birth as a potential risk factor for developing striae distensae.
- To assess the prevalence of SD in women with a history of premature birth.
Main Methods:
- A cohort of 1336 parous women aged 18-45 was analyzed.
- Participants were categorized into two groups: born at term (n=1231) and born prematurely (n=105).
- Data collected via interviews between January 2007 and June 2009.
Main Results:
- Overall prevalence of SD was 34.6%.
- Mild SD was significantly more prevalent in women born prematurely (49.5%) versus those born at term (31.8%) (P < 0.01).
- Height, weight, gravidity, parity, and abortion history were significantly associated with SD.
Conclusions:
- Premature birth is a significant risk factor for striae distensae.
- Women born prematurely have a higher likelihood of developing SD compared to women born at term.
Related Concept Videos
01:07Teratogenicity
The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
01:20Pathophysiology of Diabetes
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility, suggesting a...
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility, suggesting a...
01:28Development of the Oral Microbiota
The establishment of the oral microbiome begins before birth, challenging the long-held belief that the fetal oral cavity is sterile. The presence of oral microbes such as Streptococcus and Fusobacterium in amniotic fluid suggests that microbial exposure may occur in utero, potentially through translocation from the maternal oral or gastrointestinal tract. This early colonization primes the neonatal immune system and sets the stage for subsequent microbial succession. Maternal health,...
01:52Regression Toward the Mean
Regression toward the mean (“RTM”) is a phenomenon in which extremely high or low values—for example, and individual’s blood pressure at a particular moment—appear closer to a group’s average upon remeasuring. Although this statistical peculiarity is the result of random error and chance, it has been problematic across various medical, scientific, financial and psychological applications. In particular, RTM, if not taken into account, can interfere when researchers try to extrapolate results...