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Treatment of Liver Metastases Using an Internal Target Volume Method for Stereotactic Body Radiotherapy
Published on: May 8, 2018
Target localization accuracy in a respiratory phantom using BrainLAB ExacTrac and 4DCT imaging.
Jason E Matney1, Brent C Parker, Daniel W Neck
1Department of Physics and Astronomy, Louisiana State University, Baton Rouge, LA 70803-4001, USA. jematney@mdanderson.org
Journal of Applied Clinical Medical Physics
|May 19, 2011
Summary
This study compared four-dimensional computed tomography (4DCT) and ExacTrac X-ray imaging for measuring internal target motion. ExacTrac demonstrated superior accuracy with minimal localization error, making it ideal for gated radiotherapy planning.
Area of Science:
- Medical Physics
- Radiotherapy Technology
Background:
- Accurate internal target motion measurement is crucial for effective gated radiotherapy.
- Four-dimensional computed tomography (4DCT) and ExacTrac X-ray imaging are used for this purpose, but their accuracy varies.
Purpose of the Study:
- To evaluate and compare the accuracy of 4DCT and ExacTrac X-ray imaging systems in measuring internal target motion using a respiratory phantom.
Main Methods:
- A respiratory phantom with a metal coil surrogate target underwent sinusoidal motion (5-25 mm amplitude, 4.0s period).
- 4DCT and ExacTrac images were acquired at specific respiratory phases.
- Coil displacements and length distortions were measured and compared to known values.
Main Results:
- ExacTrac showed a maximum localization error of 0.8 mm, while 4DCT had a maximum error of 3.5 mm.
- 4DCT exhibited significant coil length distortion (up to 8.3 mm) at mid-respiratory phases with high motion velocity.
- ExacTrac accurately localized the coil across all respiratory phases without observable distortion.
Conclusions:
- The ExacTrac X-ray imaging system provides superior accuracy for internal target motion measurement compared to 4DCT.
- ExacTrac minimizes uncertainties in target size and motion, potentially reducing internal target volume margins in gated radiotherapy.

