(±)-2-Methyl-piperazin-1-ium perchlorate.

Area of Science:

• Crystallography
• Chemical Physics
• Materials Science

Background:

• Piperazine derivatives are important in medicinal chemistry and materials science.
• Understanding the solid-state structure of protonated piperazines is crucial for predicting their properties.

Purpose of the Study:

• To elucidate the crystal structure of the monoprotonated piperazine perchlorate salt.
• To investigate the intermolecular interactions governing the solid-state arrangement.

Main Methods:

• Single-crystal X-ray diffraction was employed to determine the molecular and crystal structure.
• Analysis of hydrogen bonding networks and conformational analysis of the piperazine ring.

Main Results:

• The monoprotonated piperazine cation adopts a chair conformation.
• Intermolecular N-H⋯O and N-H⋯N hydrogen bonds were identified.
• These interactions organize the cations and anions into layers parallel to the (01) crystallographic plane.

Conclusions:

• The study provides detailed structural insights into piperazine perchlorate.
• The observed hydrogen bonding pattern dictates the formation of layered supramolecular structures.
• This structural information can inform the design of new materials based on piperazine.