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Updated: Jun 1, 2026
![Microwave-assisted One-pot Synthesis of N-succinimidyl-4-[18F]fluorobenzoate ([18F]SFB)](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F2755.jpg&w=3840&q=50)
Microwave-assisted One-pot Synthesis of N-succinimidyl-4-[18F]fluorobenzoate ([18F]SFB)
Published on: June 28, 2011
4-Amino-3-ammonio-benzene-sulfonate
This study describes the crystal structure of a sulfonate-aminium zwitterion. Intermolecular hydrogen bonds form a 3D network, stabilizing the crystal packing.
Area of Science:
- Crystallography
- Chemical physics
Background:
- Zwitterions are neutral molecules with distinct positive and negative charges.
- Sulfonate groups are common functional groups in organic chemistry.
Purpose of the Study:
- To elucidate the crystal structure of the title compound, C(6)H(8)N(2)O(3)S.
- To investigate the intermolecular interactions within the crystal lattice.
Main Methods:
- Single-crystal X-ray diffraction was employed to determine the molecular and crystal structure.
- Analysis of hydrogen bonding networks was performed.
Main Results:
- The compound crystallized as a sulfonate-aminium zwitterion.
- Intermolecular N-H⋯O hydrogen bonds were identified.
- These interactions form an extensive three-dimensional network.
Conclusions:
- The zwitterionic nature of the compound is confirmed by its crystal structure.
- The 3D hydrogen bonding network plays a crucial role in stabilizing the crystal packing.
- This structural information provides insights into the solid-state behavior of such compounds.
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