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Updated: Jun 1, 2026

Imaging In-Stent Restenosis: An Inexpensive, Reliable, and Rapid Preclinical Model
Published on: September 14, 2009
[Accuracy of the 64 multislice computed tomography in the diagnosis of coronary stent restenosis]
Vladimir Mendoza-Rodríguez1, Luís R Llerena, Eddy W Olivares-Olivares
1Departamento de Tomografía Multicorte. Instituto Nacional de Cardiología y Cirugía Cardiovascular. Ciudad de La Habana, Cuba.
Objective:
To determine the accuracy of coronary angiography through 64-slice computed tomography in detecting in-stent restenosis.
Method:
Fifty-two patients with 76 coronary stents and suspicion of restenosis were examined. Initially, they underwent coronary angiography through 64-slice computed tomography, and subsequently invasive coronary angiography as gold standard. Diagnostic efficiency indexes were calculated.
Results:
In the stents of 3 mm or more of diameter, tomography sensitivity, specificity, positive and negative predictive value were 95, 98, 95 and 98% respectively, with positive likelihood ratio of 42 (CI95%, 6 to 290) and negative of 0.05 (CI95%, .01 to .35), validity of 97% and Kappa of 0.93 (CI95%, .83 to 1), (p ? 0.00001). In the stents smaller than 3 mm, the indexes of diagnostic efficiency and Kappa considerably decreased, loosing the statistical significance (p >0.05).
Conclusions:
Coronary angiography through 64-slice computed tomography is an accurate, non-invasive clinical technique for the detection of in-stent restenosis, especially with stents of 3 mm or more of diameter, and reliable allows identification of patients who need to undergo or not control invasive coronary angiography.
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