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An unusual presentation of Hodgkin's disease

C Harper1, T Evans, J Mansi

  • 1ST GEORGE HOSP,SCH MED,DEPT MED ONCOL,LONDON SW17 0RE,ENGLAND.

Oncology Reports
|May 20, 2011
PubMed

Insights

Malignant heart involvement is rare in advanced cancers. This case highlights uncommon myocardial ischemia in a young man with Hodgkin

Area of Science:

  • Cardiology
  • Oncology
  • Pathology

Background:

  • Malignant involvement of the heart and pericardium is infrequent in advanced cancers.
  • Cardiac symptoms resulting from such involvement are rare.
  • Myocardial ischemia secondary to metastatic disease is particularly uncommon.

Purpose of the Study:

  • To report a rare case of myocardial ischemia.
  • To investigate the association between myocardial ischemia and Hodgkin's disease.
  • To describe the resolution of cardiac symptoms with lymphoma treatment.

Main Methods:

  • Case report of a young male patient.
  • Diagnosis of myocardial ischemia at presentation.
  • Monitoring of cardiac status during chemotherapy for Hodgkin's disease.

Main Results:

  • Myocardial ischemia was diagnosed in a young man presenting with Hodgkin's disease.
  • The patient's myocardial ischemia resolved.
  • Resolution of ischemia correlated with the response of the underlying lymphoma to chemotherapy.

Conclusions:

  • Hodgkin's disease can present with myocardial ischemia, although rare.
  • Chemotherapy effective against lymphoma can lead to the resolution of associated cardiac conditions.
  • This case underscores the importance of considering uncommon presentations of cancer-related cardiac complications.

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