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Updated: Jun 1, 2026

Measuring the Rate of Lipolysis in Ex Vivo Murine Adipose Tissue and Primary Preadipocytes Differentiated In Vitro
Published on: March 17, 2023
The Role of Phospholipase A(2)-derived Mediators in Obesity
Marcia J Abbott1, Tianyi Tang, Hei Sook Sul
1Department of Nutritional Science and Toxicology, University of California, Berkeley, CA 94720 USA.
Abstract:
Obesity has become an epidemic and its prevalence is increasing exponentially. A great deal of focus has been given to understanding the molecular processes that regulate obesity. The characterization of phospholipase A(2)s, especially adipose-specific PLA(2), have lead to a proposed role of their downstream products in the progression of obesity and obesity related disorders. This review summarizes recent developments in the role of PLA(2) and their downstream effects in the development of metabolic disorders.
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