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Antigenic Liposomes for Generation of Disease-specific Antibodies
Published on: October 25, 2018
Immunology of allergy
Minka Schofield1, Karen H Calhoun
1The Eye and Ear Institute, Department of Otolaryngology-Head and Neck Surgery, The Ohio State University Medical Center, Columbus, OH 43212, USA.
Otolaryngologic Clinics of North America
|May 31, 2011
Summary
This review updates knowledge on allergy mechanisms, detailing immune cells and mediators involved in allergic reactions. It also explores how specific immunotherapy offers a potential cure for allergies.
Area of Science:
- Immunology
- Allergology
Background:
- Advances in immunology are rapidly expanding our understanding of allergic diseases.
- Allergic reactions involve complex interactions between immune cells and mediators.
Purpose of the Study:
- To provide an updated overview of the cellular and molecular players in allergy.
- To elucidate the mechanisms underlying allergic responses.
- To discuss the potential of specific immunotherapy as a curative treatment for allergy.
Main Methods:
- Review of current scientific literature on allergy.
- Analysis of the roles of immune cells and mediators in allergic reactions.
- Examination of the efficacy of specific immunotherapy.
Main Results:
- Detailed description of key immune cells (e.g., mast cells, T cells) and mediators (e.g., histamine, cytokines) in allergy.
- Explanation of the intricate pathways leading to allergic inflammation.
- Evidence supporting specific immunotherapy's ability to induce tolerance and potentially cure allergy.
Conclusions:
- A comprehensive understanding of allergy pathogenesis is crucial for developing effective treatments.
- Specific immunotherapy represents a promising therapeutic strategy for achieving long-term remission or cure of allergic conditions.
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