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Updated: Jun 1, 2026
07:45
Minimally Invasive Murine Laryngoscopy for Close-Up Imaging of Laryngeal Motion During Breathing and Swallowing
Published on: December 1, 2023
Frame by frame analysis of glottic insufficiency using laryngovideostroboscopy
Thomas L Carroll1, Yi-Hsuan E Wu, Marissa McRay
1The Center for Voice and Swallowing, Tufts Medical Center, 800 Washington Street, Boston, MA 02111, USA. tcarroll@tuftsmedicalcenter.org
Summary
Frame by frame analysis (FBFA) offers an objective method to detect subtle glottic insufficiency (GI) by measuring vocal fold closure duration. This technique aids in diagnosing conditions like vocal fold atrophy and paresis.
Area of Science:
- Otolaryngology
- Speech Pathology
- Medical Imaging Analysis
Background:
- Subtle glottic insufficiency (GI) presents diagnostic challenges.
- Laryngovideostroboscopy (LVS) may show incomplete vocal fold closure.
- Objective measures are needed to enhance subtle GI diagnosis.
Purpose of the Study:
- To present the frame by frame analysis (FBFA) technique.
- To evaluate FBFA's effectiveness in diagnosing subtle GI.
- To compare FBFA findings in patients with vocal fold atrophy/paresis and healthy volunteers.
Main Methods:
- Retrospective review and technique demonstration.
- Application of FBFA to 44 patients with diagnosed GI (atrophy/paresis) and 5 normal volunteers.
- Quantification of the average percentage of closed frames per glottic cycle using FBFA.
Main Results:
- Subjects with vocal fold atrophy averaged 32.4% closed frames.
- Subjects with vocal fold paresis averaged 35.7% closed frames.
- Normal volunteers averaged 50.2% closed frames.
Conclusions:
- FBFA provides a simple, objective method for suspecting subtle GI.
- The technique assists both novice and experienced LVS interpreters.
- Further validation with high-speed digital imaging is recommended.
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