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Updated: Jun 1, 2026

Automated Hydrophobic Interaction Chromatography Column Selection for Use in Protein Purification
Published on: September 21, 2011
Hydrophilic interaction liquid chromatography in food analysis
José Bernal1, Ana M Ares, Jaroslav Pól
1I. U. CINQUIMA, Analytical Chemistry Group, University of Valladolid, E. 47071 Valladolid, Spain. jose.bernal@qa.uva.es
Hydrophilic interaction liquid chromatography (HILIC) is a powerful technique for analyzing complex food samples. This review highlights HILIC
Area of Science:
- Analytical Chemistry
- Food Science
Background:
- Hydrophilic interaction liquid chromatography (HILIC) has emerged as a key technique in food analysis.
- Understanding HILIC mechanisms is crucial for optimizing separations.
Purpose of the Study:
- To review the applications of HILIC in food analysis over the past decade.
- To provide a comprehensive overview of HILIC for separating diverse food matrices.
Main Methods:
- Review of scientific literature focusing on HILIC applications in food analysis.
- Categorization of food matrices into animal origin, vegetables/fruits, and other related types.
Main Results:
- HILIC is effective for separating various food components.
- Detailed applications and results are presented for different food categories.
- Experimental conditions for key applications are summarized.
Conclusions:
- HILIC offers significant advantages for food analysis.
- This review provides a valuable resource for researchers in the field.
- The 100 references offer a comprehensive insight into HILIC applications.
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