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Updated: Jun 1, 2026

Differential Effects of Lipid-lowering Drugs in Modulating Morphology of Cholesterol Particles
Published on: November 10, 2017
[Statins can maybe reduce the risk of venous thromboembolism]
Anne Pernille Toft-Petersen1, Reimar Wernich Thomsen, Erik Berg Schmidt
1Kardiologisk Afdeling, Aarhus Universitetshospital, Aalborg Sygehus, 9100 Aalborg, Denmark.
Abstract:
Recent reports suggest beneficial effects of statin treatment on risk of venous thromboembolism (VTE). This review studies the existing literature on statins and VTE: one meta-analysis, one randomized controlled trial, four cohort studies and eight case-control studies. The hypothesis of a risk reducing effect of statins on recurrent VTE is supported, but the included studies are heterogeneous; and there is a risk of uncontrolled confounding. Randomized clinical trials aimed at clarifying whether statins can prevent recurrent VTE or not are warranted.
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