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Related Experiment Video

Updated: Jun 1, 2026

Fabrication of polydimethylsiloxane (PDMS)-Based Flexible Surface-Enhanced Raman Scattering (SERS) Substrate for Ultrasensitive Detection
03:33

Fabrication of polydimethylsiloxane (PDMS)-Based Flexible Surface-Enhanced Raman Scattering (SERS) Substrate for Ultrasensitive Detection

Published on: November 17, 2023

Large area flexible SERS active substrates using engineered nanostructures.

Aram J Chung1, Yun Suk Huh, David Erickson

  • 1Sibley School of Mechanical and Aerospace Engineering, Cornell University, Ithaca, NY 14853, USA.

Nanoscale
|June 2, 2011
PubMed
Summary
This summary is machine-generated.

Researchers developed a cost-effective shadow mask assisted evaporation (SMAE) technique for creating large, flexible surface-enhanced Raman scattering (SERS) substrates. This method enables diverse nanostructure fabrication for enhanced sensing applications.

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Ultrafast Laser-Ablated Nanoparticles and Nanostructures for Surface-Enhanced Raman Scattering-Based Sensing Applications

Published on: June 16, 2023

Area of Science:

  • Materials Science
  • Analytical Chemistry
  • Nanotechnology

Background:

  • Surface-enhanced Raman scattering (SERS) offers sensitive, label-free molecular detection.
  • SERS relies on electromagnetic field amplification from metallic nanostructures exciting surface plasmon modes.
  • Current SERS substrates often lack flexibility and large-area scalability.

Purpose of the Study:

  • To develop a simple, cost-effective method for fabricating large-area, flexible SERS-active substrates.
  • To demonstrate the fabrication of various nanostructure arrays using the new technique.
  • To investigate the SERS enhancement capabilities of hybrid nanostructures.

Main Methods:

  • Utilized shadow mask assisted evaporation (SMAE) for controlled metal deposition.
  • Employed anodized alumina nanoporous membranes (up to 27 mm) as templates.
  • Varied evaporation angle, substrate rotation, and deposition rate to control nanostructure morphology (pillar, nib, ellipsoidal cylinder, triangular tip).
  • Fabricated hybrid structures with gold nanospheres embedded in silver nano-pillars.

Main Results:

  • Successfully created four distinct nanostructure array types via SMAE.
  • Demonstrated the fabrication of flexible, large-area SERS-active substrates.
  • Achieved a 50x SERS enhancement from a hybrid gold-silver nanostructure compared to gold nanoparticles alone.

Conclusions:

  • SMAE is a versatile and cost-effective technique for producing advanced SERS substrates.
  • Flexible, large-area SERS substrates open possibilities for multiplexing and integration onto irregular surfaces.
  • Hybrid nanostructures show significant potential for boosting SERS sensitivity.