A web-based genetic polymorphism learning approach for high school students and science teachers*

Area of Science:

• Genetics and Genomics Education
• Bioinformatics in High School Curricula

Background:

• Genetics and genomics are foundational biological disciplines.
• High school students require a solid understanding of variation and polymorphism.

Purpose of the Study:

• To develop a web-based genetics education program for high school teachers and students.
• To utilize bioinformatics tools for teaching DNA variation and single nucleotide polymorphisms.

Main Methods:

• A 2-4 week web-based program was implemented for 25 teachers and 60 students.
• Freely available bioinformatics tools were used to detect single nucleotide polymorphisms and their functional effects.
• Participants learned to evaluate DNA variation and polymorphism.

Main Results:

• 70% of participating teachers developed web-based modules on DNA variation and its influence on other disciplines.
• Former students showed increased interest, with 5 entering Ph.D. programs and 80% pursuing biology or pre-med majors.
• The exercise proved simple, low-cost, and effective in fostering interest in biological sciences.

Conclusions:

• Web-based bioinformatics exercises can effectively teach genetics concepts like DNA variation.
• Such programs can inspire students to pursue careers in biology and related scientific fields.
• This approach can help establish a strong foundation for future scientists and address potential controversy surrounding evolution in curricula.