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Force generation: ATP-powered proteasomes pull the rope.

Yves F Dufrêne1, Daniel J Müller

  • 1Institute of Condensed Matter and Nanosciences, Université catholique de Louvain, Croix du Sud 2/18, B-1348 Louvain-la-Neuve, Belgium. Yves.Dufrene@uclouvain.be

Current Biology : CB
|June 7, 2011
PubMed
Summary

Single-molecule force spectroscopy reveals how an ATP-fueled machine uses mechanical forces to unfold and move protein substrates. This study offers new insights into protein unfolding and translocation mechanisms.

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