[Associated factors for sleep apnea in heart failure]
G Tsémo Watchueng1, C Mouly-Bertin, C Depagne
1Service de pneumologie, hôpital de la Croix-Rousse, Lyon, France. ghistw@yahoo.fr
Insights
Sleep apnoea syndrome (SAS) in chronic heart failure (CHF) is linked to higher left ventricular pressures. Central sleep apnoea (CSA) patients show a worse functional state than obstructive sleep apnoea (OSA) patients.
Area of Science:
- Cardiology
- Sleep Medicine
- Pulmonology
Background:
- Sleep apnoea syndrome (SAS) is common in chronic heart failure (CHF), but its origins are not fully understood.
- Understanding associated factors and differentiating between central sleep apnoea (CSA) and obstructive sleep apnoea (OSA) in CHF patients is crucial for management.
Purpose of the Study:
- To identify factors associated with SAS in patients with heart failure (HF).
- To compare the characteristics of central sleep apnoea (CSA) and obstructive sleep apnoea (OSA) within the heart failure population.
Main Methods:
- A cross-sectional, retrospective study involving 30 patients with stable heart failure on optimal medical therapy.
- Data collection included polygraphy, echocardiography, and cardiopulmonary exercise testing.
Main Results:
- SAS was present in 60% of patients (33.3% CSA, 26.7% OSA).
- Higher body mass index, blood pressure, and left ventricular pressures (E/Ea ratio) were associated with SAS.
- CSA patients exhibited higher New York Heart Association class and lower peak VO2 compared to OSA patients.
Conclusions:
- Elevated left ventricular pressures, indicated by the E/Ea ratio, are significantly associated with SAS in heart failure patients.
- Central sleep apnoea (CSA) appears to be linked to a poorer functional status in heart failure compared to obstructive sleep apnoea (OSA).
Objective:
Genesis of sleep apnoea syndrome (SAS) in chronic heart failure (CHF) is not well known. The aim of our study was to find associated factors to SAS in heart failure (HF) and to look for differences between central sleep apnea (CSA) and obstructive sleep apnea (OSA).
Patients And Methods:
We realised a cross-sectional and retrospective study. Thirty patients with stable heart failure under medical optimal therapy were included. Polygraphy, echocardiography and cardiopulmonary exercise were systematically performed.
Results:
Men were predominant (80%) in the group. Mean age, left ventricular ejection fraction (LVEF) were respectively 64.1±13.8years and 40±9.8%. SAS was present in 60% of patients (33.3% were classified as central sleep apnoea [CSA] and 26.7% as obstructive sleep apnoea [OSA]). Body mass index, blood pressure and left ventricular pressures estimated by the E/Ea ratio were significantly higher in the group with SAS (P<0.05) compared to the non SAS group. New York Heart Association class was significantly higher (P=0.04) and the predicted peak VO(2) was significantly lower in CSA patients compared to OSA patients.
Conclusion:
High left ventricular pressures estimated by the E/Ea are significantly associated with SAS in heart failure. CSA patients tend to have a worse functional state than OSA patients.
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