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Development and Functionalization of Electrolyte-Gated Graphene Field-Effect Transistor for Biomarker Detection
Published on: February 1, 2022
Recent advances in graphene-based biosensors
Tapas Kuila1, Saswata Bose, Partha Khanra
1Department of BIN Fusion Technology, Chonbuk National University, Jeonju, Jeonbuk 561-756, Republic of Korea.
Biosensors & Bioelectronics
|June 21, 2011
Summary
Graphene biosensors offer sensitive and selective detection of biomolecules like glucose and heavy metal ions. Their excellent conductivity and large surface area enable advanced sensor applications with high performance and stability.
Area of Science:
- Materials Science
- Nanotechnology
- Biomedical Engineering
Background:
- Graphene's unique properties, including large surface area and electrical conductivity, make it ideal for biosensor applications.
- Graphene acts as an efficient electron transfer mediator between biomolecules and electrode surfaces.
Purpose of the Study:
- To review the advancements in graphene-based biosensors.
- To highlight the diverse applications of graphene in detecting various biomolecules and analytes.
Main Methods:
- Review of literature on graphene-based biosensor fabrication and performance.
- Discussion of graphene oxide (GO) and reduced graphene oxide (RGO) in sensor development.
- Analysis of graphene-based field-effect transistors (FETs) for biosensing.
Main Results:
- Graphene biosensors demonstrate high sensitivity, low detection limits, and long-term stability.
- Applications include the detection of glucose, proteins (Cyt-c, Hb), cholesterol, and neurotransmitters (NADH, AA, UA, DA).
- Graphene-based sensors are effective for heavy metal ions, gases, and DNA detection.
Conclusions:
- Graphene-based biosensors represent a significant advancement in analytical technology.
- Their performance characteristics enable accurate and selective detection across a wide range of applications.
