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Label-free flow cytometry using multiplex coherent anti-Stokes Raman scattering (MCARS) for the analysis of

Charles H Camp1, Siva Yegnanarayanan, Ali A Eftekhar

  • 1School of Electrical and Computer Engineering, Georgia Institute of Technology, 777 Atlantic Drive, Atlanta, Georgia 30332, USA.

Optics Letters
|June 21, 2011
PubMed

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The development of flow cytometry techniques began in 1934 with initial attempts by Andrew Moldavan, a bacteriologist who counted the cells in a flowing capillary system. Moldavan pumped cells through a capillary tube focused under a microscope for visualization. The invention of photometry allowed the measurement of differentially-stained cells, and Louis Kamentsky developed the first multiparameter flow cytometer in 1965 to identify and count the cancer cells in cervical tissue specimens.
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