Related Experiment Video
Updated: May 31, 2026

Microfluidic Production of Lysolipid-Containing Temperature-Sensitive Liposomes
Published on: March 3, 2020
Preparation and influencing factors of sirolimus liposome by supercritical fluid
Wei Zhang1, Yong Sun, Yongjian Li
1Faculty of Pharmacy, Medical College, Qingdao University, Qingdao City, Shandong, China.
Abstract:
We prepared the sirolimus liposome by rapid expansion of supercritical solution (RESS) technology of supercritical fluid, and studied the effects of temperature, pressure, and equilibrium time on the average particle size and envelop rate of liposome. The conditions of the minimal average particle size of liposome were 328K of temperature (35MPa), 35MPa of pressure (333K), and 50 minutes of equilibrium (343K) time, respectively. The conditions of the maximal envelop rate of liposome were 333K of temperature (30MPa), 35MPa of pressure (343K), and 50 minutes of equilibrium (323K) time, respectively.
More Related Videos
08:44Preparation, Administration, and Assessment of In Vivo Tissue-Specific Cellular Uptake of Fluorescent Dye-Labeled Liposomes
Published on: July 30, 2020
08:53Synthesis, Functionalization, and Characterization of Fusogenic Porous Silicon Nanoparticles for Oligonucleotide Delivery
Published on: April 16, 2019
Related Concept Videos
Factors Affecting Dissolution: Drug Permeability, Stability and Stereochemistry
Supercritical Fluid Chromatography
SFC utilizes a supercritical fluid mobile phase,...
Bioavailability Enhancement: Drug Solubility Enhancement
Factors Influencing Drug Absorption: Pharmaceutical Parameters