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Identification of a novel HLA-B allele, B*35:01:25, by sequence-based typing in a Korean individual

M-Y Lee1, S H Oh, H R Kim

  • 1Department of Laboratory Medicine, Inje University College of Medicine, Busan, South Korea.

Tissue Antigens
|June 29, 2011
PubMed

Abstract:

The new allele B*35:01:25 showed a single nucleotide substitution compared with B*35:01:01 at codon 238 (GAT/GAC).

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Human blood is classified into different types based on the presence of antigens on the red blood cell's surface and antibodies in the plasma. Proper identification of blood type is essential for successful blood transfusion. The International Society of Blood Transfusion has identified 38 human blood types based on the surface antigens on the red blood cells. The most common types are ABO, Rh, and MNS blood types.
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