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Related Experiment Video

Updated: May 31, 2026

Measuring Pressure Volume Loops in the Mouse
09:15

Measuring Pressure Volume Loops in the Mouse

Published on: May 2, 2016

Vector volume manometry--methods and normal values.

A M P Schizas1, A V Emmanuel, A B Williams

  • 1Department of Colorectal Surgery, Guy's and St Thomas' Hospitals NHS Foundation Trust, London, UK. aschizas@doctors.net.uk

Neurogastroenterology and Motility
|July 5, 2011
PubMed
Summary
This summary is machine-generated.

Vector volume manometry (VVM) techniques were compared for fecal incontinence assessment. Faster puller speeds and 8-channel catheters improved repeatability, aiding diagnostic utility.

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Area of Science:

  • Gastroenterology
  • Physiology
  • Medical Devices

Background:

  • Vector volume manometry (VVM) is used for fecal incontinence assessment.
  • Current VVM techniques lack standardization for anal canal evaluation.
  • This study aimed to establish repeatable VVM techniques and normal values.

Purpose of the Study:

  • To assess different vector volume manometry (VVM) techniques for anal canal evaluation.
  • To determine optimal parameters for repeatable VVM results.
  • To generate normative data for VVM profiles.

Main Methods:

  • Anal canal VVM performed on 24 healthy volunteers (12 male, 12 female) using a water-perfused system.
  • Automated puller withdrawal at 3 and 25 mm/s with station technique.
  • VVM profiles analyzed using 4, 8, and 16-channel catheters.

Main Results:

  • Faster puller speed (25 mm/s) and 8-channel catheters yielded the highest VVM profile repeatability.
  • Men exhibited higher squeeze volumes and pressures; women showed greater anal canal asymmetry.
  • Station technique resulted in significantly higher squeeze vector volume and pressures.

Conclusions:

  • Faster puller speed enhances VVM profile agreement, especially during contraction.
  • 8-channel catheters demonstrate the greatest agreement between VVM profiles.
  • Standardizing automated VVM improves diagnostic accuracy for incontinence.