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Updated: May 31, 2026

Electromagnetic Source Imaging in Presurgical Evaluation of Children with Drug-Resistant Epilepsy
Published on: September 20, 2024
Neuromagnetic cerebellar activation during seizures arising from the motor cortex
Ismail S Mohamed1, Hiroshi Otsubo, Paul Ferrari
1Department of Pediatrics, IWK Health Center, Dalhousie University, 5850/5980 University Ave., Halifax, NS, Canada. ismailsidky@pol.net
Abstract:
We utilized the high temporal resolution, whole head coverage and novel analysis methodology of magnetoencephalography (MEG) to record the dynamics of cerebellar activation during focal motor seizures. We analyzed ictal MEG data from a four-year old using an event-related beamformer to localize and display ictal changes over the motor cortex and cerebellum. Contralateral activation of the cerebellum was seen 14s after MEG ictal onset over the motor cortex. These findings represent the first indication of ictal activity within the cerebellum in humans, measured non-invasively with MEG.
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Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:
Major Somatic Sensory Pathways
Seizures ll: Types