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Updated: May 31, 2026

A Patient-Derived Xenograft Model for Venous Malformation
Published on: June 15, 2020
[Spontaneous regression of a giant facial hemangioma]
H Ben Hamouda1, S Ghanmi, H Soua
1Service de pédiatrie, unité de néonatologie, CHU Tahar Sfar, 5111 Mahdia, Tunisie. hechmi.benhamouda@rns.tn
Abstract:
Infantile cutaneous hemangioma is a benign vascular tumor and is very frequent in infants. The evolution is mostly favorable with spontaneous regression in 80% of cases. Clinical diagnosis is easy in its triphasic typical form with a phase of sometimes brutal postnatal growth, a phase of stabilization and a phase of slow secondary regression. We report a case of a giant facial hemangioma diagnosed at birth in full-term female newborn getting the right peri-orbital and fronto-temporal region. Initial evolution was marked by a fast increase of the tumor justifying its stake under prednisone at the age of 3 months but without improvement. At the age of 6 months, the patient was hospitalized for infection of the hemangioma with favorable evolution under oxacilline. Following evolution was marked by the total regression of the hemangioma at the age of 5 years at the price of peri-orbital cutaneous scars. We discuss here the diagnostic, therapeutic and evolutionary aspects of this pathology and review of the literature.

