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Updated: May 31, 2026
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Published on: October 12, 2012
Lichenoid tissue reaction/interface dermatitis: recognition, classification, etiology, and clinicopathological
Virendra N Sehgal1, Govind Srivastava, Sonal Sharma
1Dermato Venereology (Skin/VD) Center, Sehgal Nursing Home, Panchwati, Delhi, India. drsehgal@ndf.vsnl.net.in
Summary
Lichenoid tissue reaction, a type of interface dermatitis, encompasses various conditions like lichen planus and drug-induced reactions. This review details their clinical and histological features for easier diagnosis.
Area of Science:
- Dermatopathology
- Histology
- Clinical Dermatology
Background:
- Lichenoid tissue reaction (LTR) is a pattern of interface dermatitis.
- It includes conditions such as lichen planus and drug-induced lichenoid dermatitis.
- Understanding LTR is crucial for diagnosing various skin disorders.
Purpose of the Study:
- To describe the clinical and histological features of lichenoid tissue reactions.
- To facilitate the diagnosis of diverse conditions exhibiting LTR.
- To provide background on the lichenoid reaction pattern.
Main Methods:
- Review of clinical presentations of LTR.
- Analysis of histological findings in LTR.
- Comparison of LTR with other interface dermatitis.
Main Results:
- Detailed description of salient clinical features of LTR variants.
- Comprehensive outline of histological characteristics aiding diagnosis.
- Categorization of miscellaneous disorders showing LTR.
Conclusions:
- Accurate diagnosis of LTR requires understanding its varied presentations.
- Clinical and histological correlation is key to differentiating LTR subtypes.
- This review serves as a diagnostic aid for lichenoid tissue reactions.
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