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Coccidioidomycosis in Chennai.

K S Sunil Kumar¹, Ajay Narasimhan, Ram Gopalakrishnan

¹Department of Pathology, Apollo Hospitals, Chennai.

The Journal of the Association of Physicians of India

|July 15, 2011

Summary

This summary is machine-generated.

Coccidioidomycosis, a fungal infection, can cause rare joint inflammation called coccidioidal synovitis. This case highlights its unusual presentation in India, treated successfully with antifungal medication.

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Area of Science:

Mycology
Infectious Diseases
Rheumatology

Background:

Coccidioidomycosis is a deep fungal infection caused by Coccidioides immitis.
Disseminated coccidioidomycosis can affect any organ system.
Coccidioidal synovitis is an uncommon but severe manifestation of musculoskeletal coccidioidomycosis.

Observation:

A 68-year-old man presented with a 4-month history of elbow pain and restricted movement.
The patient underwent synovectomy, with subsequent histological and culture analysis confirming coccidioidal synovitis.
This presentation is notably rare in India.

Findings:

Histopathology and fungal culture confirmed Coccidioides immitis as the causative agent of elbow synovitis.
The patient received treatment with itraconazole, an antifungal medication.
The patient showed positive response to treatment with improvement in symptoms.

Implications:

This case underscores the importance of considering coccidioidomycosis in the differential diagnosis of deep fungal infections presenting with joint involvement, even in non-endemic regions.
Highlights the need for increased awareness and diagnostic vigilance for coccidioidal synovitis in diverse geographical locations.
Successful treatment with itraconazole suggests its efficacy in managing this rare joint manifestation.