Related Experiment Video
Updated: May 31, 2026

Identification of Virulence Markers of Mycobacterium abscessus for Intracellular Replication in Phagocytes
Published on: September 27, 2018
Fusobacterium necrophorum causing infective endocarditis and liver and splenic abscesses
Marc Zac Handler1, Benjamin Miriovsky, Howard E Gendelman
1Department of Medicine, University of Nebraska Medical Center, Omaha, NE, USA.
Abstract:
A 25-year-old male without prior co-morbidities was admitted to hospital with Fusobacterium necrophorum bacteremia, where he was found to have liver and splenic abscesses. Further evaluation with echocardiography revealed a bicuspid aortic valve with severe insufficiency and a 1.68 x 0.86 cm vegetation. The patient required abscess drainage, intravenous antimicrobial therapy and aortic valve replacement. Complete resolution of the infection was achieved after valve replacement and a prolonged course of intravenous antimicrobial therapy. A brief analysis of the patient's clinical course and review of the literature is presented.
Related Concept Videos
Endocarditis I: Introduction
Bacterial Phylum Spirochaetes
Inhalation Anthrax
Endocarditis IV: Nursing Management
Endocarditis II: Clinical Features of Infective Endocarditis
Bacterial Phylum Bacteroidota
